For healthcare professionals
Otrivine Antistin is a dual action eye drop containing two active ingredients; Xylometazoline Hydrochloride (0.05%), a long acting vasoconstrictor and Antazoline Sulphate (0.5%) which is a H1 receptor antagonist.
Xylometazoline Hydrochloride reduces eye redness.
Antazoline Sulphate has antihistaminic, anticholinergic and local anaesthetic properties. The primary mediator of inflammation in allergic conjunctivitis appears to be histamine. Antazoline reduces histamine induced responses including itching.
For local administration into the eye.
Adults: 1 or 2 drops instilled 2 - 3 times a day.
Children aged 12 years and over: 1 drop instilled 2 to 3 times a day. No specific studies are available in this patient group.
Due to possible systemic effects, Otrivine-Antistin is not recommended for use in children younger than 12 years of age.
Otrivine Antistin Eye Drops should not be used for more than seven consecutive days.
The dispenser remains sterile until the original closure is broken. Patients must be instructed to avoid allowing the tip of the dispensing container to contact the eye or surrounding structures as this may contaminate the solution.
If more than one medication needs to be instilled in the eye, an interval of at least 5 minutes between application of the different medicinal products must be allowed.
Shelf life is 28 days after opening.
1 x 10ml Polyethylene dropper bottle.
RRP £5.48 for one bottle
PIP code: 020-5682
Page last updated: 23rd July 2024